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Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain and Illness by Jon Kabat-Zinn. Kabat-Zinn’s foundational research on mindfulness-based stress reduction provides the most research-grounded available account of the mindfulness practices that directly address the hypervigilance and threat-sensitivity that the Masi meta-analysis identifies as the loneliness-maintaining mechanism. His account of how sustained mindfulness practice reduces the automatic identification with threat-interpretation patterns, creating the observational capacity that allows the nervous system to respond to available social cues without the negativity bias that chronic loneliness produces, is the most thoroughly research-supported available treatment of the foundational cognitive intervention that the loneliness intervention literature identifies as the active ingredient. For the founder who has tried increasing social activity and found it has not addressed the loneliness they carry into each social context, Kabat-Zinn’s account of how to work with the cognitive and physiological state from the inside is the most evidence-grounded available starting point.